Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked randomized clinical trial. The purpose of this study is to compare glaucoma drainage device (GDD) implantation with the drainage tube placed in the anterior chamber (front part of the eye) or the sulcus (small space between iris and lens of the eye) in efforts to minimize corneal cell loss in the eye.
A total of about 226 patients will be enrolled in the study at 6 clinical centers: